Lithium hydroxide, monohydrate → CID 53416564

HRID 324406노트

반응식

HRID 324406 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([O:15]C)=[O:14])[CH:6]=[CH:7][CH:8]=1.O.[OH-].[Li+]>CO.O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([OH:15])=[O:14])[CH:6]=[CH:7][CH:8]=1

참가 물질

5

반응물 2

HCID 168937Lithium hydroxide, monohydrateHCID 71366468Methyl 5-(3-methoxyphenyl)penta-2,4-dienoate

생성물 1

HCID 53416564CID 53416564

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

A mixture of the product from step (i) (53.2 g) and lithium hydroxide monohydrate (52 g) in methanol (250 ml) and water (100 ml) was stirred at room temperature for 24 hours and partitioned between ethyl acetate and 2M HCl. The organic phase was washed with brine, dried (MgSO4), and evaporated under reduced pressure to afford an orange oil.

후처리

  1. custompartitioned between ethyl acetate and 2M HCl
  2. washThe organic phase was washed with brine
  3. dry with materialdried (MgSO4)
  4. customevaporated under reduced pressure
  5. customto afford an orange oil

출처 및 근거

ORD 기록
ord-b14c1bd298ba46eb80b47bab84b4d6c7
출처 데이터셋
uspto-grants-2001_04
특허 번호
US06218376B1

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