Hydrochloric Acid → S-methyl-L-cysteine ethylamide hydrochloride

HRID 325325노트

반응식

HRID 325325 반응식
[ClH:1].[CH2:2]([NH:4][C:5](=[O:18])[C@H:6]([CH2:15][S:16][CH3:17])[NH:7]C(OCCCC)=O)[CH3:3]>C(OCC)(=O)C>[ClH:1].[CH2:2]([NH:4][C:5](=[O:18])[C@H:6]([CH2:15][S:16][CH3:17])[NH2:7])[CH3:3]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 57312465S-methyl-N-butyloxycarbonyl-L-cysteine ethylamide

생성물 1

HCID 86739336S-methyl-L-cysteine ethylamide hydrochloride수율 94%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매2회

실험 절차

To 60 ml of ice-cooled 16% solution of hydrogen chloride in ethyl acetate was added dropwise a solution of 3.93 g (15 mmole) of S-methyl-N-butyloxycarbonyl-L-cysteine ethylamide in 60 ml of ethyl acetate over 20 minutes. After stirring for 2 hours, the reaction mixture was concentrated in vacuo and the residual oil was treated with ethyl ether to give 2.8 g (94% yield) of S-methyl-L-cysteine ethylamide hydrochloride as powder.

후처리

  1. concentrationthe reaction mixture was concentrated in vacuo
  2. additionthe residual oil was treated with ethyl ether

출처 및 근거

ORD 기록
ord-f4ecd067f5454a37ad5c0649b6210e4c
출처 데이터셋
uspto-grants-1984_04
특허 번호
US04440788

반응 노트

불러오는 중…