Ethylamine → N-(N-Acetyl-S-ethyl-L-cysteinyl)pyrrolidine

HRID 325335

반응식

CS[CH2:3][C@@H:4](C(O)=O)[NH:5][C:6](=O)[CH3:7].C(N)C.[CH2:15]([S:17][CH2:18][C@@H:19]([C:24]([OH:26])=O)[NH:20][C:21](=[O:23])[CH3:22])[CH3:16].N1CCCC1>>[C:21]([NH:20][C@H:19]([C:24]([N:5]1[CH2:4][CH2:3][CH2:7][CH2:6]1)=[O:26])[CH2:18][S:17][CH2:15][CH3:16])(=[O:23])[CH3:22]

참가 물질

반응물 4

HCID 6341Ethylamine

HCID 31268Pyrrolidine

HCID 147382L-Cysteine, N-acetyl-S-ethyl-

HCID 13893975N-Acetyl-S-methyl-L-cysteine

생성물 1

HCID 13048740N-(N-Acetyl-S-ethyl-L-cysteinyl)pyrrolidine

실험 절차

N-(N-Acetyl-S-ethyl-L-cysteinyl)pyrrolidine was synthesized in exactly the same manner as described in Example 14 except that the S-methyl-N-acetyl-L-cysteine and aqueous 70% ethylamine solution used in that example were replaced by S-ethyl-N-acetyl-L-cysteine and pyrrolidine, respectively.

출처 및 근거

ORD 기록: ord-43770fb6fc084cfbb9825789b5f5b43d
출처 데이터셋: uspto-grants-1984_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04440788

연결된 노트

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