Ammonium Hydroxide → 2-Amino-3-methoxybenzoic acid

HRID 325497

반응식

HRID 325497 반응식
S(S([O-])=O)([O-])=O.[Na+].[Na+].[N+:9]([C:12]1[C:20]([O:21][CH3:22])=[CH:19][CH:18]=[CH:17][C:13]=1[C:14]([OH:16])=[O:15])([O-])=O.[OH-].[NH4+]>O>[NH2:9][C:12]1[C:20]([O:21][CH3:22])=[CH:19][CH:18]=[CH:17][C:13]=1[C:14]([OH:16])=[O:15]

참가 물질

5

반응물 3

HCID 14923Ammonium HydroxideHCID 24489Sodium DithioniteHCID 786323-Methoxy-2-nitrobenzoic acid

생성물 1

HCID 2557202-Amino-3-methoxybenzoic acid

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

Sodium dithionite (84 g, 0.48 m) in water (100 ml) was added to 2-nitro-3-methoxybenzoic acid (20 g, 0.10 m) in water (100 ml)/concentrated ammonium hydroxide solution (6 ml). After stirring 3 hours the product was filtered. Acidification of the filtrate, saturation with sodium chloride and extraction with ether provided a small second crop of product.

후처리

  1. filtrationwas filtered
  2. extractionAcidification of the filtrate, saturation with sodium chloride and extraction with ether
  3. customprovided a small second crop of product

출처 및 근거

ORD 기록
ord-587c3a73c522410a8bd2eb81c7cafc00
출처 데이터셋
uspto-grants-1984_04
특허 번호
US04440941

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