1-Dodecanol → p-Dioxanone 2,5-Morpholinedione

반응식

[O:1]1[CH2:6][CH2:5][O:4][CH2:3][C:2]1=[O:7].[NH:8]1[C:13](=[O:14])[CH2:12][O:11][C:10](=[O:15])[CH2:9]1.C(O)CCCCCCCCCCC.CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2]>>[O:1]1[CH2:6][CH2:5][O:4][CH2:3][C:2]1=[O:7].[NH:8]1[C:13](=[O:14])[CH2:12][O:11][C:10](=[O:15])[CH2:9]1

참가 물질

반응물 4

HCID 81931-Dodecanol

HCID 93182-ethylhexanoic acid tin(II) salt

HCID 18233Dioxanone

HCID 1714329Morpholine-2,5-dione

생성물 1

HCID 69494823p-Dioxanone 2,5-Morpholinedione

실험 절차

p-Dioxanone (87.8 g, 0.861 moles), 2,5-morpholinedione (1.0 g, 0.0087 moles), 1-dodecanol (0.27 g, 0.00145 moles) and a catalytic amount of stannous octoate (0.176 ml of 0.33 M toluene solution, 0.000058 moles) are heated and magnetically mixed in a flame and vacuum dried, sealed glass ampoule according to the following temperature/time scheme: