Sulfur Dioxide → 1-Bromo-4-(2-methylpropyl)benzene

HRID 326029

반응식

[Br:1]N1C(=O)CCC1=O.S(=O)=O.[CH2:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH:13]([CH3:15])[CH3:14]>>[Br:1][C:19]1[CH:20]=[CH:21][C:16]([CH2:12][CH:13]([CH3:15])[CH3:14])=[CH:17][CH:18]=1

참가 물질

반응물 3

HCID 1119Sulfur Dioxide

HCID 10870Isobutylbenzene

HCID 67184N-bromobutanimide

생성물 1

HCID 37890181-Bromo-4-(2-methylpropyl)benzene수율 2%

실험 절차

To a mixture of 1.78 g (10 milliMoles) of N-bromosuccinimide in 20 ml of liquid sulfur dioxide at -30° C. is added 1.57 ml (10.0 mMoles) of isobutylbenzene. The mixture is stirred at -30° to -18° for 65 minutes, then worked up as above. Assay gives only 2% p-bromoisobutylbenzene and 88% recovered starting isobutylbenzene, indicating that the reaction with NBS is very slow at this temperature.

출처 및 근거

ORD 기록: ord-734facad83f94c9a8653c43f855a4ed6
출처 데이터셋: uspto-grants-1984_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04443631

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