1-Bromooctane → 1-n-Octylazacyclononan-2-one

HRID 326076

반응식

HRID 326076 반응식
[H-].[Na+].[NH:3]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][C:4]1=[O:12].Br[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]>>[CH2:14]([N:3]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][C:4]1=[O:12])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

참가 물질

4

반응물 3

HCID 81401-BromooctaneHCID 13632Octahydro-2H-azonin-2-oneHCID 24758Sodium hydride2회

생성물 1

HCID 128332661-n-Octylazacyclononan-2-one수율 70%

실험 절차

Following example 17, 4.2 g of 50% sodium hydride-mineral oil dispersion (2.1 g NaH, 0.0875 M), 10 g (0.0708 M) of azacyclononan-2-one and 15 g (0.0777 M) of 1-bromooctane gave 12.5 g (70%) of product; b.p. 150°-160°/0.5 mm.

출처 및 근거

ORD 기록
ord-d69b35b6ef3f46b5be418a26b3725173
출처 데이터셋
uspto-grants-1984_04
특허 번호
US04444762

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