Benzyl Alcohol → Benzyl 3-oxo-5-phenylpentanoate

HRID 326196

반응식

HRID 326196 반응식
[O:1]=[C:2]([CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].C(O)[C:18]1[CH:23]=[CH:22]C=[CH:20][CH:19]=1>C(O)C>[O:1]=[C:2]([CH2:9][CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[CH2:3][C:4]([O:6][CH2:7][C:8]1[CH:22]=[CH:23][CH:18]=[CH:19][CH:20]=1)=[O:5]

참가 물질

4

반응물 2

HCID 244Benzyl AlcoholHCID 61162Ethyl 3-oxo-5-phenylpentanoate

생성물 1

HCID 13055807Benzyl 3-oxo-5-phenylpentanoate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Ethyl 3-oxo-5-phenylpentanoate (64.2 g, 0.29 mole) was heated between 190° and 210° C. under nitrogen with benzyl alcohol (28.9 ml, 0.28 mole) for 6 hours, the ethanol formed being distilled out of the reaction mixture. The resulting pale yellow oil was essentially pure product, slightly contaminated by starting materials, n.m.r. δ(CCl4) 7.23 (5H, s), 7.06 (5H, s), 5.03 (2H, s), 3.23 (2H, s) and 2.73 (4H, s).

후처리

  1. distillationbeing distilled out of the reaction mixture

출처 및 근거

ORD 기록
ord-f813d5d350fc4144b00499e53ec2a0bc
출처 데이터셋
uspto-grants-1984_04
특허 번호
US04444981

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