Gentamicin Sulfate → Gentamicin C1

HRID 326524

반응식

HRID 326524 반응식
CC(N)[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3OC[C@@](O)(C)[C@H](NC)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)CC1.[CH3:33][CH:34]([NH:64][CH3:65])[C@H:35]1[O:40][C@H:39]([O:41][C@H:42]2[C@H:47]([OH:48])[C@@H:46]([O:49][C@H:50]3[O:55][CH2:54][C@@:53]([OH:57])([CH3:56])[C@H:52]([NH:58][CH3:59])[C@H:51]3[OH:60])[C@H:45]([NH2:61])[CH2:44][C@@H:43]2[NH2:62])[C@H:38]([NH2:63])[CH2:37][CH2:36]1.C[C@@]1(O)[C@H](NC)[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H](N)C[C@H]2N)OC1.OS(O)(=O)=O>O>[CH3:33][C@@H:34]([NH:64][CH3:65])[C@H:35]1[O:40][C@H:39]([O:41][C@H:42]2[C@H:47]([OH:48])[C@@H:46]([O:49][C@H:50]3[O:55][CH2:54][C@@:53]([OH:57])([CH3:56])[C@H:52]([NH:58][CH3:59])[C@H:51]3[OH:60])[C@H:45]([NH2:61])[CH2:44][C@@H:43]2[NH2:62])[C@H:38]([NH2:63])[CH2:37][CH2:36]1

참가 물질

3

반응물 1

HCID 9855350Gentamicin Sulfate

생성물 1

HCID 72395Gentamicin C1

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Foam wound materials containing gentamicin sulfate were prepared as shown in Example 1. Once materials were prepared they were placed onto grid supports and maintained at room temperature. All were covered with a foil wrap. Every 12 hours for nine days, 5 ml of water was applied onto the foam bandage materials and eluent was collected. Two ml samples containing SDMC entrapped gentamicin were assayed for gentamicin antibiotic activity using standard antimicrobial assays. The results are shown in Table X.

후처리

  1. customwere prepared
  2. customOnce materials were prepared they
  3. customwas collected
  4. additionTwo ml samples containing SDMC

출처 및 근거

ORD 기록
ord-61ffb64a2f9e4313bead49399f835953
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05269979

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