Acetic Anhydride → 19-Acetoxyandrost-4-en-3,17-dione

HRID 326984

반응식

HRID 326984 반응식
[OH:1][CH2:2][C@@:3]12[C@@H:20]3[C@H:11]([C@H:12]4[C@@:16]([CH2:18][CH2:19]3)([CH3:17])[C:15](=[O:21])[CH2:14][CH2:13]4)[CH2:10][CH2:9][C:8]1=[CH:7][C:6](=[O:22])[CH2:5][CH2:4]2.[C:23](OC(=O)C)(=[O:25])[CH3:24]>N1C=CC=CC=1>[C:23]([O:1][CH2:2][C@@:3]12[C@@H:20]3[C@H:11]([C@H:12]4[C@@:16]([CH2:18][CH2:19]3)([CH3:17])[C:15](=[O:21])[CH2:14][CH2:13]4)[CH2:10][CH2:9][C:8]1=[CH:7][C:6](=[O:22])[CH2:5][CH2:4]2)(=[O:25])[CH3:24]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 25237919-Hydroxyandrostenedione

생성물 1

HCID 1294241219-Acetoxyandrost-4-en-3,17-dione

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Androst-4-en-19-ol-3,17-dione (11) is treated with acetic anhydride (Ac2O, b) in pyridine. Aqueous work-up is followed by extraction and purification to yield the acetate (14).

후처리

  1. extractionAqueous work-up is followed by extraction and purification

출처 및 근거

ORD 기록
ord-7fda3844403d4eed8d5f46d4eaae5408
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05272134

연결된 노트

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