Aniline → N-Phenylphthalimide

HRID 327300

반응식

HRID 327300 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8]1(=O)[O:13][C:11](=[O:12])[C:10]2=[CH:14][CH:15]=[CH:16][CH:17]=[C:9]12>C(O)(=O)C>[C:2]1([N:1]2[C:11](=[O:12])[C:10]3=[CH:14][CH:15]=[CH:16][CH:17]=[C:9]3[C:8]2=[O:13])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 6115AnilineHCID 6811Phthalic Anhydride

생성물 1

HCID 68215N-Phenylphthalimide

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

The reaction of aniline 3.8 g (0.041 mol) with phthalic anhydride 4.0 g (0.041) mol in 100 ml of refluxing glacial acetic acid for 3 hours, followed by precipitation from water, filtration and vacuum drying at 120° C., afforded an 8.2 g (91%) yield of product, m.p. 205°-9° C. (from ethanol). Lit. reports m.p. 210° C. ("Dict. Org. Cpds", 5, 2740(1965), Oxford Univ. Press, N.Y.). Anal. Calcd. for C14H9NO2 : C, 75.33; H, 4.06. Found: C, 75.10; H, 4.17%. Ir(KBr): 1765, 1700, and 1375 cm-1 (imide).

후처리

  1. customfollowed by precipitation from water, filtration and vacuum
  2. customdrying at 120° C.
  3. customafforded an 8.2 g (91%) yield of product, m.p. 205°-9° C. (from ethanol)

출처 및 근거

ORD 기록
ord-fdd9f9ff61c947a19ee3c1e9f453229c
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05272248

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