Potassium ethylxanthate → HCID 178505573, 화합물

HRID 327779

반응식

HRID 327779 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[NH2:9].CCO[C:13]([S-])=[S:14].[K+]>C(O)C.O>[F:8][C:4]1[C:3]2[N:9]=[C:13]([SH:14])[NH:1][C:2]=2[CH:7]=[CH:6][CH:5]=1

참가 물질

5

반응물 2

HCID 2735045Potassium ethylxanthateHCID 27828353-Fluorobenzene-1,2-diamine

생성물 1

HCID 178505573HCID 178505573, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

1,2-diamino-3-fluorobenzene (1.6 g, 12.7 mmol) and potassium ethyl xanthogenate (2.64 g, 16.5 mmol) were dissolved in ethanol (25 ml) and water (6 ml). The mixture was refluxed for 14 hours and then concentrated on a rotavapor. Water (20 ml) was added and the solution was acidified with 2M hydrochloric acid. The precipitate was filtered off and dried. In this way the title compound was obtained (1.23 g, 58%). NMR is given below.

후처리

  1. temperatureThe mixture was refluxed for 14 hours
  2. concentrationconcentrated on a rotavapor
  3. additionWater (20 ml) was added
  4. filtrationThe precipitate was filtered off
  5. customdried

출처 및 근거

ORD 기록
ord-40645df9b5a5419f897a6ce588ca7b3d
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05274099

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