Triethylamine → HCID 21444454, 화합물

HRID 328231노트

반응식

HRID 328231 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][C:8]1[C:13]([CH3:14])=[CH:12][C:11]([OH:15])=[CH:10][C:9]=1[CH3:16].[CH3:17][N:18]=[C:19]=[O:20].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:17][NH:18][C:19](=[O:20])[O:15][C:11]1[CH:10]=[C:9]([CH3:16])[C:8]([S:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)=[C:13]([CH3:14])[CH:12]=1

참가 물질

5

반응물 3

HCID 8471Triethylamine2회HCID 12228Methyl Isocyanate2회HCID 214444563,5-Dimethyl-4-[(pyridin-2-yl)sulfanyl]phenol

생성물 1

HCID 21444454HCID 21444454, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

4-(2-Pyridylthio)-3,5-dimethylphenol (161 g.), prepared in part A, and methylisocyanate (48 g.) was dissolved in dry toluene (1500 ml.) containing triethylamine (10 ml.) and the mixture was then stirred under reflux overnight. Further quantities of methyl isocyanate (22 g.) and triethylamine (10 ml.) were then added and refluxing was continued for a further 6 hours.

후처리

  1. temperatureunder reflux overnight
  2. temperaturerefluxing

출처 및 근거

ORD 기록
ord-f3409fc254964ee69152ca37335f6d2d
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04016278

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