Methane → 2-(4-Heptyl-4-piperidyloxy)-ethanol

HRID 329035

반응식

HRID 329035 반응식
C([N:8]1[CH2:13][CH2:12][C:11]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([O:14][CH2:15][CH2:16][OH:17])[CH2:10][CH2:9]1)C1C=CC=CC=1.[H][H].C>C(O)C>[CH2:18]([C:11]1([O:14][CH2:15][CH2:16][OH:17])[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

참가 물질

5

반응물 3

HCID 297MethaneHCID 214409382-(1-Benzyl-4-heptyl-4-piperidyloxy)-ethanolHCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 214409012-(4-Heptyl-4-piperidyloxy)-ethanol수율 36.3%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 40 g of 2-(1-benzyl-4-heptyl-4-piperidyloxy)-ethanol in 300 ml of absolute ethanol was reacted with hydrogen at 50° C in the presence of 0.4 g of 5% palladized charcoal until the theoretical amount of hydrogen was absorbed and the catalyst was then filtered off. The ethanol was distilled off and the residue was rectified to obtain 10.6 g of 2-(4-heptyl-4-piperidyloxy)-ethanol as a colorless oil boiling at 110°-130° C at 0.1 mm Hg.

후처리

  1. customwas absorbed
  2. filtrationthe catalyst was then filtered off
  3. distillationThe ethanol was distilled off

출처 및 근거

ORD 기록
ord-6f91d58563e24e39beddfffdeb6cce77
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04018922

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