1,3-Propanediamine → N-(3-aminopropyl)pyrimidin-2-amine

HRID 329085

반응식

HRID 329085 반응식
Br[C:2]1[N:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:8][CH2:9][CH2:10][CH2:11][NH2:12].[O-]CC.[Na+]>C(O)C>[NH2:8][CH2:9][CH2:10][CH2:11][NH:12][C:2]1[N:7]=[CH:6][CH:5]=[CH:4][N:3]=1

참가 물질

5

반응물 3

HCID 4281,3-PropanediamineHCID 783452-BromopyrimidineHCID 2723922Sodium ethoxide

생성물 1

HCID 14397405N-(3-aminopropyl)pyrimidin-2-amine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Reaction of 2-bromopyrimidine with 1,3-diaminopropane in ethanol containing sodium ethoxide gives 2-(3-aminopropylamino)pyrimidine which on reaction with methyl isothiocyanate results in the production of N-methyl-N'-[3-(2 -pyrimidylamino)propyl]thiourea.

출처 및 근거

ORD 기록
ord-107e0288ee52418c9f3854597503d573
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04018931

연결된 노트

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