Hydrochloric Acid → 4-(dimethylamino)-2-hydroxybenzaldehyde

HRID 329206노트

반응식

HRID 329206 반응식
[OH:1][C:2]1[CH:7]=[C:6]([N:8]([CH3:10])[CH3:9])[CH:5]=[CH:4][C:3]=1[CH:11]1N(C2C=CC=CC=2)CCN1C1C=CC=CC=1.Cl.[OH2:29]>C(O)C>[OH:1][C:2]1[CH:7]=[C:6]([N:8]([CH3:10])[CH3:9])[CH:5]=[CH:4][C:3]=1[CH:11]=[O:29]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 12265340HCID 12265340, 화합물

생성물 1

HCID 98153054-(dimethylamino)-2-hydroxybenzaldehyde

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The reaction product (XV) obtained in accordance with Example 16 is suspended in warm ethanol. A clear solution is formed, following the addition of 5 ml of 5% aqueous hydrochloric acid. 10 ml of water are added and the aqueous solution is extracted by repeated shaking with 10 ml batches of chloroform. After the chloroform has been distilled off in vacuo from the combined chloroform extracts, 2-hydroxy-4-dimethylaminobenzaldehyde (XVI) is obtained in the form of pale yellow needles, melting at 77° to 78° C.

후처리

  1. customA clear solution is formed
  2. extractionthe aqueous solution is extracted
  3. distillationAfter the chloroform has been distilled off in vacuo from the combined chloroform

출처 및 근거

ORD 기록
ord-2d017c238cd14073a1c6107aa6c5a48d
출처 데이터셋
uspto-grants-1977_04
특허 번호
US04020084

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