Hydrochloric Acid → N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

HRID 329757

반응식

HRID 329757 반응식
C[Al](C)C.Cl.[CH2:6]([O:8][NH2:9])[CH3:7].[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31](OC)=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1.Cl>C(Cl)Cl>[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31]([NH:9][O:8][CH2:6][CH3:7])=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 52997Sulfometuron-methylHCID 76850O-ethylhydroxylamine hydrochlorideHCID 16682925Trimethylaluminum

생성물 1

HCID 19871558N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To 2.9 g of trimethylaluminum in 100 ml of methylene chloride is added 2.0 g of ethoxyamine hydrochloride with stirring at ambient temperature. To this mixture is added 3.0 g of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide and the solution is refluxed for 18 hours. The reaction mixture is treated with aqueous hydrochloric acid and the resulting precipitated product is purified by chromatography.

후처리

  1. temperaturethe solution is refluxed for 18 hours
  2. customthe resulting precipitated product
  3. customis purified by chromatography

출처 및 근거

ORD 기록
ord-a3ef8abf81d14e7cb104d6a293d44aef
출처 데이터셋
uspto-grants-1990_01
특허 번호
US04892946

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