Dimethylformamide → (3-Methyl-but-3-enyloxymethyl)-benzene

HRID 332071노트

반응식

HRID 332071 반응식
[CH:1]1[CH:6]=[CH:5][C:4]([CH2:7]Br)=[CH:3][CH:2]=1.[H-].[Na+].CN([CH:14]=[O:15])C>>[CH3:5][C:4](=[CH2:3])[CH2:7][CH2:14][O:15][CH2:7][C:4]1[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1

참가 물질

4

반응물 3

HCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 24758Sodium hydride

생성물 1

HCID 11095166(3-Methyl-but-3-enyloxymethyl)-benzene

실험 절차

BnBr was added to the mixture of alcohol and NaH in DMF cooled in an ice bath. The mixture was stirred at room temperature overnight and the solid was filtered. The solvent was removed and the residue was purified by column chromatography to give compound 1.

후처리

  1. temperaturecooled in an ice bath
  2. filtrationthe solid was filtered
  3. customThe solvent was removed
  4. customthe residue was purified by column chromatography

출처 및 근거

ORD 기록
ord-8b3cf9473ad641549a850aaa49a84708
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08877796B2

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