Trimethylsilyldiazomethane → Methyl 5-formyl-2-furoate

HRID 332587

반응식

HRID 332587 반응식
[CH:1]([C:3]1[O:7][C:6]([C:8]([OH:10])=[O:9])=[CH:5][CH:4]=1)=[O:2].[CH3:11][Si](C=[N+]=[N-])(C)C>CC(C)=O>[CH3:11][O:9][C:8]([C:6]1[O:7][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=1)=[O:10]

참가 물질

4

반응물 2

HCID 167693TrimethylsilyldiazomethaneHCID 27937195-Formyl-2-furancarboxylic Acid

생성물 1

HCID 12283779Methyl 5-formyl-2-furoate

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

5-Formyl-2-furancarboxylic acid (5 g, 35.7 mmol) was dissolved in acetone (100 mL), and trimethylsilyl-diazomethane/2M hexane solution (23.2 mL, 46.4 mmol) was slowly added dropwise at room temperature. After stirring at room temperature for 10 minutes, the solvent was evaporated under reduced pressure to give 5-formyl-2-furancarboxylic acid methyl ester as a crude product.

후처리

  1. customthe solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-f7bcdd8ed3a44b75afc4740aea08f9ad
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08877805B2

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