Triphenylstannane → HCID 11152734, 화합물

HRID 333641

반응식

HRID 333641 반응식
C1(C)C(C)=CC=CC=1.C1([SnH](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:28]([C:31]1[CH:36]=[CH:35][C:34]([N:37]=[N:38][C:39](=[C:43]2[C:52]3[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=3)[CH2:46][C:45]([CH3:54])([CH3:53])[NH:44]2)[C:40]([NH2:42])=[O:41])=[CH:33][CH:32]=1)(=[O:30])[CH3:29]>C(#N)C>[C:28]([C:31]1[CH:32]=[CH:33][C:34]([N:37]=[N:38][CH:39]([CH:43]2[C:52]3[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=3)[CH2:46][C:45]([CH3:54])([CH3:53])[NH:44]2)[C:40]([NH2:42])=[O:41])=[CH:35][CH:36]=1)(=[O:30])[CH3:29]

참가 물질

5

반응물 3

HCID 6460TriphenylstannaneHCID 7237O-XyleneHCID 178466770HCID 178466770, 화합물

생성물 1

HCID 11152734HCID 11152734, 화합물

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

In a nitrogen atmosphere, 2-(4-acetyl-phenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinoline-1-ylidene)-acetamide (Asinex Corp., Russia) is dissolved in acetonitrile, and the obtained product is added with xylene in which triphenyl tin hydride (Aldrich, Corp., USA) is dissolved, and the mixture is refluxed. The refluxed product is cooled to room temperature and an insoluble matter is separated by filtration. The solvent is removed from the filtrate by reducing the pressure. The residue containing the reaction product is purified by column chromatography to obtain the title compound.

후처리

  1. dissolutionis dissolved
  2. temperaturethe mixture is refluxed
  3. customan insoluble matter is separated by filtration
  4. customThe solvent is removed from the filtrate
  5. additionThe residue containing the reaction product
  6. customis purified by column chromatography

출처 및 근거

ORD 기록
ord-ce31b888ce6146548f9a61256b784f0d
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883504B2

연결된 노트

불러오는 중…