4-Fluoro-3-nitrobenzotrifluoride → Tert-butyl [3-methyl-3-(2-nitro-4-trifluoromethyl-phenylamino)-butyl]-carbamate
반응식
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[NH2:15][C:16]([CH3:28])([CH3:27])[CH2:17][CH2:18][NH:19][C:20](=[O:26])[O:21][C:22]([CH3:25])([CH3:24])[CH3:23]>>[CH3:28][C:16]([NH:15][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])([CH3:27])[CH2:17][CH2:18][NH:19][C:20](=[O:26])[O:21][C:22]([CH3:24])([CH3:23])[CH3:25]참가 물질
3
실험 절차
This is prepared analogously to method 2a) from a total of 3.25 g (15.5 mmol) 1-fluoro-2-nitro-4-trifluoromethyl-benzene and 2.74 g (13.5 mmol) tert-butyl (3-amino-3-methyl-butyl)-carbamate. 6.1 g yellow oil. Mass spectroscopy: [M+H]+=392.
출처 및 근거
- ORD 기록
- ord-466c0b33939342febed166262092aff5
- 출처 데이터셋
- uspto-grants-2008_09