4-Fluoro-3-nitrobenzotrifluoride → Tert-butyl [3-methyl-3-(2-nitro-4-trifluoromethyl-phenylamino)-butyl]-carbamate

HRID 33368

반응식

HRID 33368 반응식
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[NH2:15][C:16]([CH3:28])([CH3:27])[CH2:17][CH2:18][NH:19][C:20](=[O:26])[O:21][C:22]([CH3:25])([CH3:24])[CH3:23]>>[CH3:28][C:16]([NH:15][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])([CH3:27])[CH2:17][CH2:18][NH:19][C:20](=[O:26])[O:21][C:22]([CH3:24])([CH3:23])[CH3:25]

참가 물질

3

반응물 2

HCID 677784-Fluoro-3-nitrobenzotrifluorideHCID 45072486tert-butyl N-(3-amino-3-methylbutyl)carbamate

생성물 1

HCID 86603968Tert-butyl [3-methyl-3-(2-nitro-4-trifluoromethyl-phenylamino)-butyl]-carbamate

실험 절차

This is prepared analogously to method 2a) from a total of 3.25 g (15.5 mmol) 1-fluoro-2-nitro-4-trifluoromethyl-benzene and 2.74 g (13.5 mmol) tert-butyl (3-amino-3-methyl-butyl)-carbamate. 6.1 g yellow oil. Mass spectroscopy: [M+H]+=392.

출처 및 근거

ORD 기록
ord-466c0b33939342febed166262092aff5
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429583B2

연결된 노트

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