Iodoethane → 5-[2-(2,4-Dichloro-phenyl)-propionyl]-1-ethyl-1H-pyridin-2-one

HRID 333866노트

반응식

HRID 333866 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH3:19])[C:10]([C:12]1[CH:13]=[CH:14][C:15](=[O:18])[NH:16][CH:17]=1)=[O:11].I[CH2:21][CH3:22]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH3:19])[C:10]([C:12]1[CH:13]=[CH:14][C:15](=[O:18])[N:16]([CH2:21][CH3:22])[CH:17]=1)=[O:11]

참가 물질

3

반응물 2

HCID 6340IodoethaneHCID 574213545-[2-(2,4-Dichloro-phenyl)-propionyl]-1H-pyridin-2-one

생성물 1

HCID 668132695-[2-(2,4-Dichloro-phenyl)-propionyl]-1-ethyl-1H-pyridin-2-one

실험 절차

In analogy to Example 195, 5-[2-(2,4-dichloro-phenyl)-propionyl]-1H-pyridin-2-one (Example 201, step 4) was alkylated with iodoethane to give the title compound as a colorless oil. MS (m/e)=324.2 [M+H+].

출처 및 근거

ORD 기록
ord-7e83f78891dc48a193bcaa7517fa5bce
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883786B2

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