Hydrochloric Acid → HCID 68273173, 화합물

HRID 334840

반응식

HRID 334840 반응식
[N:1]1[N:2]([C:10]2[CH:15]=[C:14]([C:16]([CH3:23])([CH3:22])[CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:13]=[CH:12][C:11]=2O)[N:3]=[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=12.[CH2:25]=[O:26].[ClH:27]>C(O)(=O)C.[Cl-].[Zn+2].[Cl-]>[N:1]1[N:2]([C:10]2[CH:15]=[C:14]([C:16]([CH3:23])([CH3:22])[CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:13]=[C:12]([CH2:11][Cl:27])[C:25]=2[OH:26])[N:3]=[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=12

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 62485Octrizole

생성물 1

HCID 68273173HCID 68273173, 화합물

시약·촉매·용매 2

HCID 3007855Zincchloride촉매HCID 176Acetic Acid용매

실험 절차

2-(2H-Benzotriazol-2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol (45.0 g, 140 mmol) is dissolved in acetic acid (200 mL) at 90° C. Zinc chloride (2.0 g, 14 mmol) and paraformaldehyde (18 g, 600 mmol) are added and HCl gas is passed through the reaction mixture for 12 hours at 90° C. The product, which precipitates after cooling to room temperature, is filtered off, washed with cold pentane and dried at 60° C. under vacuum to yield 36 g of 2-(2H-Benzotriazol-2-yl)-6-chloromethyl-4-(1,1,3,3-tetramethyl-butyl)-phenol.

후처리

  1. customThe product, which precipitates
  2. filtrationis filtered off
  3. washwashed with cold pentane
  4. customdried at 60° C. under vacuum

출처 및 근거

ORD 기록
ord-5d8960d93a87475bb6d1bad0107b651b
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08883829B2

연결된 노트

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