Sodium Hydroxide → HCID 59797443, 화합물

HRID 33800노트

반응식

HRID 33800 반응식
C[O:2][C:3](=[O:33])[CH2:4][O:5][C:6]1[C:19]2[S:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[S:11][C:10]=2[C:9]([C:20]2[O:21][C:22]([N:27]3[CH2:32][CH2:31][O:30][CH2:29][CH2:28]3)=[CH:23][C:24](=[O:26])[CH:25]=2)=[CH:8][CH:7]=1.[OH-].[Na+:35]>CO>[Na+:35].[N:27]1([C:22]2[O:21][C:20]([C:9]3[C:10]4[S:11][C:12]5[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=5)[S:18][C:19]=4[C:6]([O:5][CH2:4][C:3]([O-:33])=[O:2])=[CH:7][CH:8]=3)=[CH:25][C:24](=[O:26])[CH:23]=2)[CH2:32][CH2:31][O:30][CH2:29][CH2:28]1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 59797432[4-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-1-yloxy]-acetic acid methyl ester

생성물 1

HCID 59797443HCID 59797443, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of [4-(6-Morpholin-4-yl-4-oxo-4H-pyran-2-yl)-thianthren-1-yloxy]-acetic acid methyl ester (1.41 g, 2.91 mmol) in anhydrous methanol (10 ml) was added sodium hydroxide (120 mg, 2.91 mmol) in a single portion. The solution was then stirred at room temperature for 24 hours whereupon the solvent was removed in vacuo to give the title compound as an off white paste (1.43 g, 98%) that required no further purification. m/z (LC-MS, ESP): RT=3.79 min, (M−−23)=468

후처리

  1. customwas removed in vacuo

출처 및 근거

ORD 기록
ord-e52a91aebc534d4dacbd50f3f2e5e93f
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07429660B2

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