Methyl iodide → 4-(3-Acetylphenyl)amino-2-amino-1,6-dimethylpyrimidinium iodide

HRID 3393노트

반응식

HRID 3393 반응식
[C:1]([C:4]1[CH:5]=[C:6]([NH:10][C:11]2[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH2:18])[N:12]=2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].[CH3:19][I:20]>CC(C)=O>[I-:20].[C:1]([C:4]1[CH:5]=[C:6]([NH:10][C:11]2[CH:16]=[C:15]([CH3:17])[N+:14]([CH3:19])=[C:13]([NH2:18])[N:12]=2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 133110Cni H1594

생성물 1

HCID 120932594-(3-Acetylphenyl)amino-2-amino-1,6-dimethylpyrimidinium iodide

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Compound No. 14: 4-(3-acetylphenyl)amino-2-amino-6methylpyrimidine, Compound No. 15, (0.968 g) was suspended in acetone (5 mL) containing methyl iodide (2 mL) was heated at reflux for 48 hr. Filtration after cooling gave 0.657 g of 4-(3-acetylphenyl)amino-2-amino-1,6-dimethylpyrimidinium iodide as a white powder, mp 238°-40° C.

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 48 hr
  3. filtrationFiltration
  4. temperatureafter cooling

출처 및 근거

ORD 기록
ord-74a2ccfcddee49eb8680c2a9e7272626
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05733932

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