4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline → 4-Acetoxy-N-[4-(6-methoxybenzothiazol-2-yl)-phenyl]-benzamide

HRID 339518

반응식

HRID 339518 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:9][C:10]3[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.[C:19]([O:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][CH:24]=1)(=[O:21])[CH3:20]>N1C=CC=CC=1>[C:19]([O:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]([NH:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]3[S:9][C:10]4[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:11]=4[N:12]=3)=[CH:6][CH:7]=2)=[O:28])=[CH:25][CH:24]=1)(=[O:21])[CH3:20]

참가 물질

4

반응물 2

HCID 3918704-(6-Methoxy-1,3-benzothiazol-2-yl)anilineHCID 2756254p-Acetoxybenzoyl chloride

생성물 1

HCID 673124824-Acetoxy-N-[4-(6-methoxybenzothiazol-2-yl)-phenyl]-benzamide수율 94.3%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Prepared as described in the Amide Coupling section above using 2-(4-aminophenyl)-6-methoxybenzothiazole (0.25 g, 0.976 mmol) and 4-acetoxybenzoyl chloride (0.22 g, 1.07 mmol) in dry pyridine (10 ml) to give the title compound (0.385 g, 94%) as a colourless solid after work-up.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-af2d3d64779f46498e30f8d105d55e59
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895313B2

연결된 노트

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