4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline → HCID 67313154, 화합물

HRID 339521

반응식

HRID 339521 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:9][C:10]3[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.[CH3:19][O:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][C:22]=1[C:30]([F:33])([F:32])[F:31]>N1C=CC=CC=1>[F:31][C:30]([F:32])([F:33])[C:22]1[CH:23]=[C:24]([CH:28]=[CH:29][C:21]=1[O:20][CH3:19])[C:25]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[S:9][C:10]3[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:11]=3[N:12]=2)=[CH:6][CH:7]=1)=[O:26]

참가 물질

4

반응물 2

HCID 3918704-(6-Methoxy-1,3-benzothiazol-2-yl)anilineHCID 27752984-Methoxy-3-(trifluoromethyl)benzoyl chloride

생성물 1

HCID 67313154HCID 67313154, 화합물수율 87%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Prepared as described in the Amide Coupling section using 2-(4-aminophenyl)-6-methoxybenzothiazole (0.5 g, 1.95 mmol) and 4-methoxy-3-trifluoromethylbenzoyl chloride (0.47 g, 1.95 mmol) in dry pyridine (15 ml) to give the title compound (0.77 g, 87%) as pale yellow feathery crystals after work-up and recrystallisation from acetic acid.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-f231a315b48e409ca85777f2f217b6a9
출처 데이터셋
uspto-grants-2014_11
특허 번호
US08895313B2

연결된 노트

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