홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Water → HCID 68292717, 화합물

HRID 339906
노트
인쇄 미리보기

반응식

HRID 339906 반응식
[CH3:1][O:2][C:3]1[CH:28]=[C:27]([O:29][CH3:30])[CH:26]=[CH:25][C:4]=1[CH2:5][NH:6][S:7]([CH2:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]([N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)=O)=[CH:13][CH:12]=1)(=[O:9])=[O:8].[H-].[H-].[H-].[H-].[Li+].[Al+3].O.[OH-].[Na+]>C1COCC1>[CH3:1][O:2][C:3]1[CH:28]=[C:27]([O:29][CH3:30])[CH:26]=[CH:25][C:4]=1[CH2:5][NH:6][S:7]([CH2:10][C:11]1[CH:12]=[CH:13][C:14]([CH2:17][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)=[CH:15][CH:16]=1)(=[O:9])=[O:8]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 962Water2회HCID 14798Sodium HydroxideHCID 21226445Aluminium lithium hydrideHCID 68292273HCID 68292273, 화합물

생성물 1

HCID 68292717HCID 68292717, 화합물수율 97.5%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

To a solution of N-(2,4-dimethoxybenzyl)-C-[4-(morpholine-4-carbonyl)phenyl]methanesulfonamide (440 mg) in THF (5 ml) was added, at 0° C., LAH (96 mg), and the mixture was warmed up to room temperature and stirred for a further 60 minutes. After the addition of water (100 μl), sodium hydroxide solution (300 μl) and water again (300 μl), the mixture was filtered and the filtrate was concentrated. This gave the product (415 mg) with a molecular weight of 420.5 g/mol (C21H28N2O5S).

후처리

  1. filtrationthe mixture was filtered
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-863da2f159274db6a6cd51a4a4f334c8
출처 데이터셋
uspto-grants-2014_11
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US08895547B2

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트