Hydrochloric Acid → Hydrochloric Acid
반응식
[Si]([O:8][CH2:9][C@@H:10]([N:14](C)[C:15](=O)OC(C)(C)C)[CH2:11][CH:12]=[CH2:13])(C(C)(C)C)(C)C.[ClH:23]>CO>[CH3:15][NH:14][C@@H:10]([CH2:11][CH:12]=[CH2:13])[CH2:9][OH:8].[ClH:23]참가 물질
5
실험 절차
To a solution of (S)-tert-butyl 1-(tert-butyldimethylsilyloxy)pent-4-en-2-yl(methyl)carbamate (3.4 g, 10.3 mmol) in methanol (10 mL) was added HCl (4.0 M in 1,4-dioxane, 25 mL, 0.10 mol). The resulting solution was stirred for 2 h. The solvent was removed, and the remaining residue was dried under vacuum to give (S)-2-(methylamino)pent-4-en-1-ol as a HCl salt, which was used without further purification. LRMS (M+H+) m/z 116.2.
후처리
- customThe solvent was removed
- customthe remaining residue was dried under vacuum
출처 및 근거
- ORD 기록
- ord-fa7814db6d654b7c869034ee3122b3ea
- 출처 데이터셋
- uspto-grants-2014_11
- 특허 번호
- US08895582B2
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