Allyl bromide → 2-Propenyloxydibenzofuran

HRID 342776

반응식

HRID 342776 반응식
[OH:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1.[CH2:15](Br)[CH:16]=[CH2:17].C(=O)([O-])[O-].[K+].[K+]>>[CH:15]([O:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1)=[CH:16][CH3:17]

참가 물질

4

반응물 3

HCID 7841Allyl bromideHCID 11430Potassium CarbonateHCID 665872-Dibenzofuranol

생성물 1

HCID 572524052-Propenyloxydibenzofuran

실험 절차

A solution of 2-hydroxydibenzofuran (2.0 grams) was treated with allyl bromide (1.2 mL) and potassium carbonate (1.5 grams). The mixture was stirred over night at 60°. The reaction was partitioned between methylene chloride and water. The organic was washed once with water and dried over sodium sulfate. The organic layer was filtered and concentrated to an oil which was chromatographed over silica gel to afford the title compound.

후처리

  1. customThe reaction was partitioned between methylene chloride and water
  2. washThe organic was washed once with water
  3. dry with materialdried over sodium sulfate
  4. filtrationThe organic layer was filtered
  5. concentrationconcentrated to an oil which
  6. customwas chromatographed over silica gel

출처 및 근거

ORD 기록
ord-3e18335d1be24ab18925c6d52005670c
출처 데이터셋
uspto-grants-1999_01
특허 번호
US05859051

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