Benzaldehyde → Ethyl 2-benzylideneaminobutyrate

HRID 342865

반응식

HRID 342865 반응식
C(N(CC)CC)C.Cl.[NH2:9][CH:10]([CH2:16][CH3:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12].[CH:18](=O)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C1(C)C=CC=CC=1>[CH:18](=[N:9][CH:10]([CH2:16][CH3:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

5

반응물 3

HCID 240BenzaldehydeHCID 8471TriethylamineHCID 12844023Ethyl 2-Aminobutyrate Hydrochloride

생성물 1

HCID 10331026Ethyl 2-benzylideneaminobutyrate

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Triethylamine (2 moles) was added to a solution of the product from step (a) (1 mole) in toluene. When addition was complete, benzaldehyde (1 mole) was added. The mixture was azeotroped until no further water was collected, then cooled to room temperature and filtered. The filtrate was evaporated in vacuo ti give the desired product as an oil.

후처리

  1. additionWhen addition
  2. customThe mixture was azeotroped until no further water
  3. customwas collected
  4. filtrationfiltered
  5. customThe filtrate was evaporated in vacuo ti

출처 및 근거

ORD 기록
ord-410984a921a147c6bb9ce5296f537673
출처 데이터셋
uspto-grants-1999_01
특허 번호
US05859240

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