Acetic Anhydride → 1,1-Cyclohexanediacetic Anhydride

HRID 343462노트

반응식

HRID 343462 반응식
[C:1]1([CH2:11][C:12]([OH:14])=[O:13])([CH2:7][C:8]([OH:10])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(OC(=O)C)(=O)C>>[CH2:4]1[CH2:3][CH2:2][C:1]2([CH2:7][C:8](=[O:10])[O:14][C:12](=[O:13])[CH2:11]2)[CH2:6][CH2:5]1

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 78061Cyclohexanediacetic acid

생성물 1

HCID 27342891,1-Cyclohexanediacetic Anhydride

실험 절차

To a 100-mL round-bottomed flask was added 1,1-cyclohexanediacetic acid (2.03 g, 9.99 mmol) and acetic anhydride (11.6 mL). The reaction mixture was held at reflux for 2 hours, and then cooled to room temperature. Volatiles were removed via vacuum distillation (0.1 Torr, 20°-60° C.). The resulting crude product was dried under vacuum (0.1 Torr) at 80° C. for 14 hours to yield the title compound as a white solid which was used without further purification (1.75 g, 96%).

후처리

  1. temperatureat reflux for 2 hours
  2. customVolatiles were removed via vacuum distillation (0.1 Torr, 20°-60° C.)
  3. dry with materialThe resulting crude product was dried under vacuum (0.1 Torr) at 80° C. for 14 hours

출처 및 근거

ORD 기록
ord-7ff7af5d993847fcb2a96d3bce8e5e6a
출처 데이터셋
uspto-grants-1999_01
특허 번호
US05861428

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