Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(Indan-5-yl)-1-isopropyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | NoName_76 | HCID 414244 | — |
| 반응물 | 5-isothiocyanato-2,3-dihydro-1H-indene | HCID 2759357 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(Indan-5-yl)-1-isopropyl-2-thioxo-imidazolidin-4-one | HCID 15389491 | 36.1% |
반응 단계
The title compound was prepared by the procedure described in Example 18 using 17.5 g of indan-5-yl-isothiocyanate, 21.2 g of N-isopropyl glycine, 21.0 g of triethyl amine, and 300 mL of chloroform. Crystallization from ethanol afforded the title compound (9.9 g) as a white solid, m.p. 178°-180° C. Anal. Calcd. for. C15H18N2OS: C, 56.66; H, 6.61; N, 10.21. Found: C, 56.70; H, 6.67; N, 10.22. Mass spectrum (EI, M.+) m/z 274.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05861517 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-bbdf46dbe9fe4895bc580feea3cdef89 |
| 출처 메모 | uspto-grants-1999_01 |