Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(+/-)-5-(2,5-Dioxo-4-imidazolidinylmethyl)-3-(1-methyl-4-piperidyl)-1H-indole → (+/-)-3-[3-(1-Methyl-4-piperidyl)-1H-indol-5-yl]alanine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (+/-)-5-(2,5-Dioxo-4-imidazolidinylmethyl)-3-(1-methyl-4-piperidyl)-1H-indole | HCID 15233277 | — |
| 반응물 | Barium hydroxide, monohydrate | HCID 17749100 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | (+/-)-3-[3-(1-Methyl-4-piperidyl)-1H-indol-5-yl]alanine | HCID 22852202 | — |
반응 단계
A solution of the product from step (d) (2.4 g) and barium hydroxide hydrate (8.4 g) in water (50 ml) was refluxed for 72 hours, then cooled and evaporated in vacuo. The residue was taken up in hot methanol and filtered to remove barium salts.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05863935 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-318bfde53829421087aea779f67bc012 |
| 출처 메모 | uspto-grants-1999_01 |