Cyclohexanone → 7,12-Dioxaspiro(5,6)dodec-9-ene

HRID 344001

반응식

HRID 344001 반응식
OCC[CH:4]1[C:9]2([O:14][CH2:13][CH2:12][CH2:11][O:10]2)[CH2:8][CH2:7][CH2:6][CH2:5]1.[C:15]1(=O)CCCCC1>>[CH2:8]1[C:9]2([O:10][CH2:15][CH:11]=[CH:12][CH2:13][O:14]2)[CH2:4][CH2:5][CH2:6][CH2:7]1

참가 물질

3

반응물 2

HCID 7967CyclohexanoneHCID 86753629(2-Hydroxyethyl)-7, 11-dioxaspiro (5,5) undecane

생성물 1

HCID 2609417,12-Dioxaspiro(5,6)dodec-9-ene

실험 절차

Described herein is a process for the preparation of 9 (2-hydroxyethyl)-7, 11-dioxaspiro (5,5) undecane by reacting Cis-but-2-2ene-1,4 diol with cyclohexanone in the presence of a heterogeneous sulphonated nitro coal acid catalyst to obtain 7, 12-dioxaspiro (5,6) dodec-9-ene which is reacted with syngas in the presence of a catalyst, namely RhH (CO) (TPP)3, to obtain 9-formyl-7, 12-dioxaspiro (5,6) dodecane which is reduced and the reduced product is rearranged to yield 9-(2-hydroxyethyl)-7,11-dioxaspiro [5,5] undecane.

출처 및 근거

ORD 기록
ord-1a61910381414954be1eb828494ad0b3
출처 데이터셋
uspto-grants-1999_01
특허 번호
US05864046

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