Hydrochloric Acid → 4'-[(2-n-Butyl-6-dimethylaminoaminocarbonylamino-benzimidazol-1-yl)-methyl]-2-(1H-tetrazol-5-yl)-biphenyl
반응식
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:23]3[N:27](C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)[N:26]=[N:25][N:24]=3)=[CH:13][CH:12]=2)[C:8]2C=C[CH:49]=[C:50]([NH:51][C:52]([NH:54][N:55]([CH3:57])[CH3:56])=[O:53])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].Cl.CCO[CH2:62][CH3:63].CO.C(Cl)Cl>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:23]3[NH:27][N:26]=[N:25][N:24]=3)=[CH:15][CH:16]=2)[C:8]2[CH:7]=[C:50]([NH:51][C:52]([NH:54][N:55]([CH3:56])[CH3:57])=[O:53])[CH:49]=[CH:62][C:63]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]참가 물질
4
반응물 3
생성물 1
실험 절차
Prepared in analogous manner to Example 58b from 4'-[(2-n-butyl-4-dimethylaminoaminocarbonylamino-benzimidazol-1-yl)-methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenyl and hydrochloric acid in ether/methanol/methylene chloride.
출처 및 근거
- ORD 기록
- ord-d432a2c3c5244ace99d8b0e4d33359ee
- 출처 데이터셋
- uspto-grants-1999_01
- 특허 번호
- US05864043
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