Tetrahydrophthalic anhydride → HCID 12881900, 화합물

HRID 344592

반응식

HRID 344592 반응식
[CH2:1]1[CH:6]2[C:7]([O:9][C:10](=[O:11])[CH:5]2[CH2:4][CH:3]=[CH:2]1)=O.[CH2:12]([O:15][C:16]1[CH:17]=[C:18]([CH:20]=[CH:21][C:22]=1[Cl:23])[NH2:19])[CH:13]=[CH2:14]>C(O)(=O)C>[CH2:12]([O:15][C:16]1[CH:17]=[C:18]([N:19]2[C:10](=[O:11])[C:5]3[CH2:4][CH2:3][CH2:2][CH2:1][C:6]=3[C:7]2=[O:9])[CH:20]=[CH:21][C:22]=1[Cl:23])[CH:13]=[CH2:14]

참가 물질

4

반응물 2

HCID 6810Tetrahydrophthalic anhydrideHCID 544961134-Chloro-3-[(prop-2-en-1-yl)oxy]aniline

생성물 1

HCID 12881900HCID 12881900, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A mixture of 4.4 g of THPA, 5.3 g of 3B and 60 mL of glacial acetic acid was refluxed for 1 hour, then poured into 300 mL of ice water. The resulting mixture was allowed to stand for 10 minutes, then filtered. The collected solid was washed with cold water, dried under reduced pressure and recrystallized from ethyl acetate/hexane, to give N-(3-(allyloxy)-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide (3C), as yellow crystals, m.p.: 118.5°-120° C.

후처리

  1. temperaturewas refluxed for 1 hour
  2. filtrationfiltered
  3. washThe collected solid was washed with cold water
  4. customdried under reduced pressure
  5. customrecrystallized from ethyl acetate/hexane

출처 및 근거

ORD 기록
ord-93160ebf2a4a4814a78be9c823f58fad
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05053071

연결된 노트

불러오는 중…