N-Pyridin-4-ylacetamide → HCID 19993658, 화합물

HRID 345006

반응식

HRID 345006 반응식
[Cl:1][CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:4].[C:19]([NH:22][C:23]1[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=1)(=[O:21])[CH3:20]>C(Cl)(Cl)Cl>[Cl-:1].[C:19]([NH:22][C:23]1[CH:28]=[CH:27][N+:26]([CH2:2][C:3](=[O:4])[NH:5][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:25][CH:24]=1)(=[O:21])[CH3:20]

참가 물질

4

반응물 2

HCID 21288N-Pyridin-4-ylacetamideHCID 14819969N-(2-Anilinophenyl)-2-chloroacetamide

생성물 1

HCID 19993658HCID 19993658, 화합물

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

Dissolved in 30 ml of chloroform are 6.2 g of 2-chloro-N-[2-(phenylamino)phenyl]acetamide and 5.0 g of 4-acetylaminopyridine, and the solution is left on standing overnight. After completion of the reaction, the reaction mixture is held at 5° C. to 10° C., and left on standing at the same temperature for 5 hours. The precipitates, which separate out, are recovered by filtration and recrystallized from ethanol to give the desired compound of 4-acetylamino-1-[2-oxo-2-[[2-(phenylamino)phenyl]amino]ethyl]pyridinium chloride.

후처리

  1. waitthe solution is left
  2. customAfter completion of the reaction
  3. customis held at 5° C. to 10° C.
  4. waitleft
  5. waiton standing at the same temperature for 5 hours
  6. customThe precipitates, which separate out
  7. filtrationare recovered by filtration
  8. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-8bc1e5a5688149c7b9d2d2d68b2b3456
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05055469

연결된 노트

불러오는 중…