Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethyl orthoformate → HCID 11008070, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethyl orthoformate | HCID 9005 | — |
| 반응물 | 3-Hydroxy-2,2-dimethylpropionaldehyde | HCID 11699 | — |
| 반응물 | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| 반응물 | HCID 178418582 | HCID 178418582 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 11008070 | HCID 11008070 | — |
반응 단계
A solution of 24.4 g (0.24 mol) of 3-hydroxy-2,2-dimethylpropanal (Aldrich), 26 g (0.25 mol) of trimethyl orthoformate, and 0.5 mL of 6.8 N HCl/dioxane in 300 mL of methanol was allowed to stand at room temperature overnight. A slight excess of NaOCH3 was added and the solvent evaporated at reduced pressure. The residue was dissolved in ether and the mixture filtered. After evaporation of solvent and fractionation twice through a 15 cm Vigreux column, the product was obtained as a water white oil, bp 43°-48°/0.2mm, 18.5 g (52%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05055613 |
| 출처 데이터셋 | uspto-grants-1991_10 |
| ORD ID | ord-2c753e33e993440b831c89dc3bb7c67a |
| 출처 메모 | uspto-grants-1991_10 |