Trimethyl orthoformate → 8-Oxo-2-methoxy-3-oxa-1-azabicyclo[4.2.0]octane

HRID 345253노트

반응식

HRID 345253 반응식
[O:1]=[C:2]1[N:9]2[CH:4]([CH2:5][CH2:6][O:7][C:8]2(C)C)[CH2:3]1.[CH:12](OC)(OC)[O:13]C>>[O:1]=[C:2]1[N:9]2[CH:4]([CH2:5][CH2:6][O:7][CH:8]2[O:13][CH3:12])[CH2:3]1

참가 물질

3

반응물 2

HCID 9005Trimethyl orthoformateHCID 12769229HCID 12769229, 화합물

생성물 1

HCID 199939978-Oxo-2-methoxy-3-oxa-1-azabicyclo[4.2.0]octane

실험 절차

Following the procedure described for the preparation of 8-oxo-2,2-dimethyl-3-oxa-1-azabicyclo[4.2.0]octane from 4-(2-40 -hydroxyethyl)-2-azetidinone and using trimethyl orthoformate instead of 2,2-dimethoxypropane one obtains 8-oxo-2-methoxy-3-oxa-1-azabicyclo[4.2.0]octane.

출처 및 근거

ORD 기록
ord-aa0514d74bdf4944b75d77247b35abfd
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05055573

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