Phenylacetonitrile → 2,7-Diamino-6-phenylpyrido[2,3-d]pyrimidine

HRID 3453

반응식

[C:1]1([CH2:7][C:8]#[N:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:10][C:11]1[N:16]=[C:15]([NH2:17])[C:14]([CH:18]=O)=[CH:13][N:12]=1>>[C:1]1([C:7]2[C:8]([NH2:9])=[N:17][C:15]3[N:16]=[C:11]([NH2:10])[N:12]=[CH:13][C:14]=3[CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

반응물 2

HCID 8794Phenylacetonitrile

HCID 3091762,4-Diaminopyrimidine-5-carbaldehyde

생성물 1

HCID 108474752,7-Diamino-6-phenylpyrido[2,3-d]pyrimidine

실험 절차

Following the procedure of Example 1, phenylacetonitrile was reacted with 2,4-diamino-5-pyrimidinecarboxaldehyde to give the title compound; mp 317°-318° C.

출처 및 근거

ORD 기록: ord-8da630abf3734058b3c2ab512c708bab
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05733913

연결된 노트

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