Hydrochloric Acid → HCID 19991491, 화합물

HRID 345858

반응식

HRID 345858 반응식
[C:1]1([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH2:10][CH2:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:17](Br)[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[CH3:26][Mg]Br.[ClH:29]>C(OCC)C>[ClH:29].[CH3:26][C:7]1([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][CH2:9][N:8]1[CH2:17][CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 7666Phenethyl bromideHCID 6099261-Phenyl-3,4-dihydroisoquinolineHCID 178418573HCID 178418573, 화합물

생성물 1

HCID 19991491HCID 19991491, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

1-Methyl-1-phenyl-2-phenethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride was prepared by reacting 1-phenyl-3,4-dihydroisoquinoline with phenethyl bromide, then 3M diethyl ether solution of methylmagnesium bromide according to a similar manner to that of Example 26, and then converting the resultant compound to its hydrochloride according to a conventional manner.

출처 및 근거

ORD 기록
ord-3d18c4b4d53b4219bff15b7851121328
출처 데이터셋
uspto-grants-1991_10
특허 번호
US05059608

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