2H-Azepine, 3,4,5,6-tetrahydro-7-methoxy- → 2,4-Diamino-6-(5-aminopentyl)-1,3,5-triazine

HRID 34783

반응식

HRID 34783 반응식
[NH2:1][C:2]([NH:4][C:5]([NH2:7])=[NH:6])=[NH:3].CO[C:10]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][N:11]=1>C(O)C>[NH2:6][C:5]1[N:4]=[C:2]([NH2:1])[N:3]=[C:12]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:10][NH2:11])[N:7]=1

참가 물질

4

반응물 2

HCID 756572H-Azepine, 3,4,5,6-tetrahydro-7-methoxy-HCID 176517607Carbamimidamidomethanimidamide

생성물 1

HCID 212987902,4-Diamino-6-(5-aminopentyl)-1,3,5-triazine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of biguanide (1.05 g.), 4,5,6,7-tetrahydro-2-methoxy-3H-azepine (1.27 g.) and ethanol (50 ml.) was heated under reflux for 18 hours, cooled and the solid that crystallised was collected to give 2,4-diamino-6-(5-aminopentyl)-1,3,5-triazine which was used without further purification.

후처리

  1. temperaturewas heated
  2. temperatureunder reflux for 18 hours
  3. temperaturecooled
  4. customthe solid that crystallised
  5. customwas collected

출처 및 근거

ORD 기록
ord-d160538931fd480d9675ac1086279244
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04762932

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