Acetic Anhydride → 1,5-Diacetyl-3-(ethoxy-phenyl-methylidene)-2-indolinone

HRID 347952

반응식

HRID 347952 반응식
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13](=[O:15])[CH3:14])=[CH:10][CH:11]=2)[CH2:6][C:5]1=[O:16])(=[O:3])[CH3:2].[C:17]([O:20][C:21](=O)[CH3:22])(=O)[CH3:18]>CCOC(OCC)(OCC)C1C=CC=CC=1>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13](=[O:15])[CH3:14])=[CH:10][CH:11]=2)[C:6](=[C:17]([O:20][CH2:21][CH3:22])[C:18]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:5]1=[O:16])(=[O:3])[CH3:2]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 210845601,5-Diacetyl-2-indolinone

생성물 1

HCID 689919611,5-Diacetyl-3-(ethoxy-phenyl-methylidene)-2-indolinone

시약·촉매·용매 1

HCID 74268Benzene, (triethoxymethyl)-용매2회

실험 절차

32.6 g (150 mmol) 1,5-diacetyl-2-indolinone are suspended in 100 ml triethyl orthobenzoate and stirred overnight with 150 ml acetic anhydride at 110° C. Then a further 50 ml triethyl orthobenzoate are added and the mixture is stirred for a further 24 h. Then it is evaporated down and the resulting precipitate is suction filtered, washed and dried.

후처리

  1. customThen it is evaporated down
  2. filtrationfiltered
  3. washwashed
  4. customdried

출처 및 근거

ORD 기록
ord-05c85fbcbf0d48e6b86502da5c42840b
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07176231B2

연결된 노트

불러오는 중…