HCID 68839044, 화합물 → 4,6-Dihydrothieno(3,4-c)furan-1,3-dione
반응식
CO[C:3]([CH:5]1[CH2:9][S:8][CH2:7][C:6]1(O)[C:10]([OH:12])=[O:11])=[O:4]>C(OC(=O)C)(=O)C>[S:8]1[CH2:7][C:6]2[C:10]([O:12][C:3](=[O:4])[C:5]=2[CH2:9]1)=[O:11]참가 물질
3
실험 절차
A solution of 3-hydroxy tetrahydro thiophene-3,4-dicarboxylicacid-4-methylester (2.87 g, 14.9 mmol) in acetic anhydride (20 ml) was refluxed for 4 h. The reaction mixture was filtered and concentrated under reduce pressure. The solid residue was triturated with acetone, dried with Na2SO4 and concentrated in vacuo. The solid product was recrystallized from benzene to give 2,5-dihydrothiophene-3,4-dicarboxylic anhydride in 26% yield.
후처리
- filtrationThe reaction mixture was filtered
- concentrationconcentrated
- customThe solid residue was triturated with acetone
- dry with materialdried with Na2SO4
- concentrationconcentrated in vacuo
- customThe solid product was recrystallized from benzene
출처 및 근거
- ORD 기록
- ord-e59402433d0546e589a217e6b856568b
- 출처 데이터셋
- uspto-grants-2007_02
- 특허 번호
- US07176241B2
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