Potassium Carbonate → 4-((Allyl(methyl)amino)methyl)thiazol-2-amine

HRID 350959

반응식

HRID 350959 반응식
[CH2:1]([NH:4][CH3:5])[CH:2]=[CH2:3].Cl.[NH2:7][C:8]1[S:9][CH:10]=[C:11]([CH2:13]Cl)[N:12]=1.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH2:1]([N:4]([CH2:13][C:11]1[N:12]=[C:8]([NH2:7])[S:9][CH:10]=1)[CH3:5])[CH:2]=[CH2:3]

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 69391N-MethylallylamineHCID 732282-Thiazolamine, 4-(chloromethyl)-, hydrochloride (1:1)

생성물 1

HCID 210906034-((Allyl(methyl)amino)methyl)thiazol-2-amine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

N-allyl-N-methylamine (7.0 mg, 0.1 mmol), 2-amino-4-chloromethylthiazole hydrochloride (18.5 mg, 0.1 mmol), and potassium carbonate (30 mg, 0.21 mmol) are shaken in ethanol (1 mL) at room temperature for 18 hours. The mixture is filtered and the filtrate was condensed under vacuum.

후처리

  1. filtrationThe mixture is filtered
  2. customcondensed under vacuum

출처 및 근거

ORD 기록
ord-6de76e9d87074e8c81db3041feaa73dd
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07183300B2

연결된 노트

불러오는 중…