Propargyl bromide → Propargyl-n-tetradecylamine

HRID 352045

반응식

HRID 352045 반응식
C(=O)([O-])[O-].[Na+].[Na+].[CH2:7]([NH2:21])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[CH2:22](Br)[C:23]#[CH:24]>CC(C)=O>[CH2:24]([NH:21][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:23]#[CH:22]

참가 물질

5

반응물 3

HCID 7842Propargyl bromideHCID 10340Sodium CarbonateHCID 16217Tetradecylamine

생성물 1

HCID 22715195Propargyl-n-tetradecylamine

시약·촉매·용매 1

HCID 180Acetone용매2회

실험 절차

5 g (47 mmol) of anhydrous sodium carbonate are added to a solution of 10.0 g (47 mmol) of n-tetradecylamine in 100 ml of absolute acetone, and the suspension is heated to reflux. At that temperature 5.9 g (50 mmol) of propargyl bromide in 50 ml of acetone are then added dropwise and the mixture is subsequently heated at reflux for 2 hours. After aqueous working-up, the product is obtained in the form of a brown oil having a purity of >90%.

후처리

  1. temperaturethe suspension is heated to reflux
  2. temperaturethe mixture is subsequently heated
  3. temperatureat reflux for 2 hours
  4. customAfter aqueous working-up, the product is obtained in the form of a brown oil

출처 및 근거

ORD 기록
ord-ebe834bdf133483186173eabf48552ef
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06743940B2

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