2-Acetylfuran → HCID 535936, 화합물

반응식

[C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)(=[O:3])[CH3:2].CO[CH:11](OC)[N:12]([CH3:14])[CH3:13]>>[CH3:11][N:12]([CH3:14])[CH:13]=[CH:2][C:1]([C:4]1[O:5][CH:6]=[CH:7][CH:8]=1)=[O:3]

참가 물질

반응물 2

HCID 145052-Acetylfuran

HCID 78373Dimethylformamide dimethyl acetal

생성물 1

HCID 535936HCID 535936, 화합물수율 97%

반응 조건

온도: 100 °C

실험 절차

A mixture of 2-acetylfuran (25.0 g, 0.227 mmol) and N,N-dimethylformamide dimethylacetal (40 ml) was stirred at 100° C. for 9 hours. After cooling as it was, the reaction solution was concentrated. Diethyl ether and hexane were added to the residue, and the resulting solid was collected by filtration and washed with hexane, to give the title compound (36.5 g, 97%) as a brown solid.

후처리

temperatureAfter cooling as it
concentrationthe reaction solution was concentrated
additionDiethyl ether and hexane were added to the residue
filtrationthe resulting solid was collected by filtration
washwashed with hexane

출처 및 근거

ORD 기록: ord-f94a5246ce3443b092460200d15c6f49
출처 데이터셋: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06750232B2

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