Ethanol → HCID 22708122, 화합물

HRID 353218

반응식

HRID 353218 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6].[CH3:10][C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[CH:14]=1)=O.[OH-].[K+].C(O)C>O>[F:1][C:2]1[CH:3]=[C:4]([C:5](=[O:6])/[CH:10]=[CH:11]/[C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[CH:14]=2)[CH:7]=[CH:8][CH:9]=1

참가 물질

6

반응물 4

HCID 702EthanolHCID 99673-FluoroacetophenoneHCID 14797Potassium HydroxideHCID 680093-Fluorobenzaldehyde

생성물 1

HCID 22708122HCID 22708122, 화합물수율 93%

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

A mixture of 3-fluorobenzaldehyde (7.63 mL, 72.4 mmol), 3-fluoroacetophenone (10 g, 72.4 mmol), potassium hydroxide (5.18 g, 92.6 mmol), ethanol (23 mL) and water (47 mL) was stirred overnight at room temperature. After the reaction solution was diluted with water, the solid was collected by filtration and washed with ethanol and diethyl ether, to give the title compound (16.4 g, 93%).

후처리

  1. filtrationthe solid was collected by filtration
  2. washwashed with ethanol and diethyl ether

출처 및 근거

ORD 기록
ord-1dc89752ecc94f6f816c4c7f12c5b1be
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06750232B2

연결된 노트

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