Hydrochloric Acid → HCID 70404474, 화합물

HRID 35363노트

반응식

HRID 35363 반응식
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[O:16][CH2:15][CH2:14][C@@H:13]3[C@H:8]([O:9][CH2:10][CH2:11][NH:12]3)[C:6]=2[CH:7]=1.O1CCN[C@@H]2CCOC3C=CC=CC=3[C@@H:18]12.[ClH:32]>>[ClH:32].[F:1][C:2]1[CH:3]=[CH:4][C:5]2[O:16][CH2:15][CH2:14][C@@H:13]3[C@H:8]([O:9][CH2:10][CH2:11][N:12]3[CH3:18])[C:6]=2[CH:7]=1

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 13609762trans-3,4,4a,5,6,11b-hexahydro-2H-[1]benzoxepino[5,4-b]-1,4-oxazineHCID 14256326HCID 14256326, 화합물

생성물 1

HCID 70404474HCID 70404474, 화합물

실험 절차

In a similar way, substituting trans-10-fluoro-3,4,4a,5,6,11b-hexahydro-2H-[1]benzoxepino[5,4-b]-1,4-oxazine for the trans-3,4,4a,5,6,11b-hexahydro-2H-[1]benzoxepino[5,4-b]-1,4-oxazine above and using hydrogen chloride instead of maleic acid, results in the formation of trans-10-fluoro-3,4,4a,5,6,11b-hexahydro-4-methyl-2H-[1]benzoxepino[5,4-b]-1,4-oxazine hydrochloride having a mp. of 244°-245° C.

출처 및 근거

ORD 기록
ord-72aeb09876554aebaa614218f4d682d4
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04766212

반응 노트

불러오는 중…